Synthesis of aminoorganophosphorus compounds and study of substituent effect on biological activity

Abstract

Organophosphorus compounds have multipurpose uses such as insecticides, herbicides, fungicides and as antiviral drugs. A convenient and facile method for the synthesis of bis- (substituted phenylamino) chlorophosphine oxide have been developed by the reaction of phosphoryl chloride with substituted aromatic amine in presence of dichloro methane (DCM) at room temperature. ..................................