Abstract:
The aim of the research project is to synthesize “Thiourea based thiadiazolin derivatives” and the goal of this research was successfully performed by three different steps:
First: Thermal cyclization of thiosemicarbazide with substituted carboxylic acids to 5-phenyl 2-aminothiadiazole using catalytic amount of sulphuric acid.
Second: Various Schiff‟s bases were synthesized from 5-phenyl -2-amino-1,3,4-thiadiazole and different substituted aromatic aldehydes.
Third: Addition of ammonium thiocyanate to Schiff‟s bases afforded thioformimido thiadiazole derivatives.
The structures of all the synthesized compounds were confirmed by spectral evidence.
