Synthesis and characteriztion of some novel diazotized compounds composed of bis-iminamine moiety and evaluation of their antibacterial property

Abstract

Azo compounds are highly reactive compounds with enormous variety of applications. The azo compounds were marketed mainly in form of azo-disperse, azo-vat, azo-acid, dyes, food, cosmetic medicine, leather, plastics, varnish, automobile etc. These com-pounds are also more suitable for biocidal treatment of textile fibers due to their greater biological activities, because biocidal template forms a definite type of bonding with fi-brous material and forms important structures in the medicinal and pharmaceutical fields. The pharmacological study of these compounds started from the effect of antibacterial action of Prontosil on streptococcal infections by Dog-magk. It is evident from the litera-ture that these kinds of functionalities have great potential to be used as antibacterial as well as antioxidant agents. At the same time these compounds are used as an important synthetic precursor. On this point of view, we have designed and successfully synthesized some novel diazotized compounds composed of bis-iminamine moiety by following diazo coupling reaction between diazonium salts and active methylene compounds. All the compounds are characterized by IR, 1H NMR and 13C NMR spectral evidences. The syn-thesized compounds are summarized in the following tables.