Synthesis and characterization of metallodendrimers containing nickel using 2,4,6-tri amino pyrimidine

Abstract

In the light of precedent and current developments, there is preference for the development of new bioorganometallic metallodendrimers. Dendrimers and Metallodendrimers are highly branched, globular, multivalent, monodisperse three dimensional fractal like macromolecules with synthetic resourcefulness and many promising applications ranging from catalysis to electronics and drug delivery. Because of multipurpose applications it was intended to expand a method to synthesis nickel containing metallodendrimer molecules using 2,4,6-triaminopyrimidine or Diazine.

At first, a suitable process for the synthesis of metallodendrimer compounds 7-11was developed from the reaction of diazine (pyrimidine) with different aroylchlorides 2-6 in presence of (Ph3P)2NiBr2 at room temperature as shown in the scheme 1.

Scheme: 1

2, 7 R = C6H4CH3(p) 3, 8 R = C6H4NO2 (p) 4, 9 R = C6H5 5, 10 R= C6H4Cl (p) 6, 11 R = C6H4OCH3 (p)

The synthesized compounds were characterized by IR, 1H NMR, 13C NMR spectrophotometry to establish the structure. SEM was taken for analysis of surface morphology. The Compounds were found having a homogeneous and non‐homogeneous morphology with the particle size range from 100 μm to 500 μm. The particle size detected by SEM indicated that the molecule was supramolecule.